U-shaped-aggressiveness of SARS-CoV-2: Period between initial symptoms and clinical progression to COVID-19 suspicion. A population-based cohort study.

BackgroundEarly identification of different COVID-19 clinical presentations may depict distinct pathophysiological mechanisms and guide management strategies.ObjectiveTo determine the aggressiveness of SARS-CoV-2 using symptom progression in COVID-19 patients.DesignHistoric cohort study of Mexican patients.Data from January-April 2020 were provided

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